SANTA FE, Texas (AP) — At least one gunman opened fire at a Houston-area high school Friday, killing eight to 10 people, most of them students, authorities said.

Harris County Sheriff Ed Gonzalez said he could not be precise about the number of deaths at Santa Fe High School, which went on lockdown around 8 a.m. Two suspects believed to be students were in custody.

It was the nation's deadliest school shooting since the February attack in Parkland, Florida, that killed 17 people and re-energized the gun-control movement after surviving teens launched a campaign for reform.

The school district confirmed an unspecified number of injuries but said it would not immediately release further details. A school police officer was being treated at a hospital, the sheriff said, but there was no immediate word on the extent of his injuries.

"We hope the worst is over, and I really can't say any more about that because it would be pure speculation," Assistant Principal Cris Richardson Richardson told reporters at the scene.

Aerial footage showed students standing in a grassy field and three medical helicopters landing at the school in Santa Fe, a city of about 13,000 residents roughly 30 miles (48 kilometers) southeast of Houston.

School officials said law enforcement officers were working to secure the building and move students to another location. Students were being transported to another location to reunite with their parents.

One student told Houston television station KTRK in a telephone interview that a gunman came into her first-period art class and started shooting. The student said she saw one girl with blood on her leg as the class evacuated the room.

"We thought it was a fire drill at first but really, the teacher said, 'Start running,'" the student told the television station.

The student said she did not get a good look at the shooter because she was running away. She said students escaped through a door at the back of the classroom.

Authorities did not immediately confirm that report.