Willi Castro had the game-ending sacrifice fly with the bases loaded in the ninth, lifting the Twins to a 7-6 comeback victory over the Cleveland Guardians on Thursday night.
Bailey Ober allowed one run in six innings, Kyle Farmer homered and drove in three runs, and the Minnesota Twins beat Los Angeles 5-1 on Tuesday night.
Ryan (5-0) joined Jerry Koosman in 1979 as the only Twins pitchers to win their first five starts since the franchise moved to Minnesota for the 1961 season.